10 mg lyophilised · single compound (small molecule, not a peptide)
$55.00 CAD
5-Amino-1MQ is a small research molecule that blocks NNMT, an enzyme involved in how cells manage energy and store fat. It is used as a research tool to explore metabolism, fat-cell biology, and the NAD+ pathway linked to cellular ageing.
For laboratory and research use only - not for human consumption.
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View previous lab results5-Amino-1MQ is a small synthetic molecule - not a peptide - that blocks the enzyme NNMT (nicotinamide N-methyltransferase). Enzymes are biological catalysts; NNMT helps control how cells use certain methyl groups and the vitamin-B3 pathway that feeds NAD+ (a coenzyme central to how cells make and use energy).
Research is preclinical (cell and animal studies), centred on metabolism. In diet-induced obese mice, NNMT inhibitors reduced body weight and fat-tissue (adipose) mass without changing how much the animals ate, and raised cellular NAD+ levels. It is widely used as a tool to study fat-cell (adipocyte) biology, energy expenditure, and the NAD+ pathway (linked to cellular ageing).
By inhibiting NNMT, 5-Amino-1MQ is thought to slow the “using up” of nicotinamide (a NAD+ precursor) and of methyl groups, shifting the cell toward higher NAD+ and an altered methylation balance - changes associated in models with greater energy use in fat cells.
5-Amino-1MQ is not an approved medicine in any jurisdiction, and the supporting data are preclinical. Supplied strictly as a research compound - not for human consumption.
A single vial containing 10 mg of 5-Amino-1MQ as a lyophilised powder.
